Serglycin in human cancers
نویسندگان
چکیده
منابع مشابه
Serglycin in human cancers
Serglycin belongs to a family of small proteoglycans with Ser-Gly dipeptide repeats, and it is modified with different types of glycosaminoglycan side chains. Intracellular serglycin affects the retention and secretion of proteases, chemokines, or other cytokines by physically binding to these factors in secretory granules. Extracellular serglycin has been found to be released by several types ...
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Serglycin is a major proteoglycan of hematopoietic cells. It is thought to play a role in the packaging of granule proteins in human neutrophil granulocytes. The presence of serglycin in myeloid cells has been demonstrated only at the transcriptional level. We generated a polyclonal antibody against recombinant human serglycin. Here, we show the localization of serglycin in humans during neutro...
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ژورنال
عنوان ژورنال: Chinese Journal of Cancer
سال: 2011
ISSN: 1000-467X,1944-446X
DOI: 10.5732/cjc.011.10314